OpenEvidence

About OpenEvidence

OpenEvidence is a medical search platform that aggregates peer-reviewed research and clinical guidelines into a single search interface. Users can ask clinical questions in natural language and receive synthesized answers with inline citations linking to original studies in sources like PubMed, NEJM, JAMA, and Lancet. Instead of manually reviewing abstracts and studies, clinicians get concise summaries of evidence, including where consensus or disagreement exists. The platform also includes Visits, an ambient documentation feature that records and transcribes patient encounters to generate clinical notes. Some institutions, such as Cedars-Sinai, have integrated OpenEvidence directly into their EHR systems, allowing clinicians to pull evidence relevant to specific patient charts. Access requires verification of medical credentials, such as an NPI number, and the core platform is free for U.S. healthcare professionals, supported by advertising from pharmaceutical and medical device companies. OpenEvidence was founded in 2021 and is backed by Sequoia and Google.

Key features

• ✓Natural language clinical question input
• ✓Synthesized answers with inline citations to primary literature
• ✓Coverage of major medical journals (NEJM, JAMA, Lancet, PubMed)
• ✓Ambient documentation feature (Visits) for clinical note generation
• ✓EHR integration for patient-specific evidence retrieval
• ✓Free for verified U.S. healthcare professionals
• ✓NPI verification required for access
• ✓Ad-supported revenue model

Use cases

• ✓Clinical decision support at the point of care
• ✓Drug information lookup and comparison
• ✓Medical literature search and guideline review

Frequently asked questions about OpenEvidence